KMID : 0370220160600050261
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Yakhak Hoeji 2016 Volume.60 No. 5 p.261 ~ p.264
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Practical Synthesis of a Natural Hydroxycinnamide Derived from Hippophae rhamnoides L.
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Han Young-Taek
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Abstract
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A practical synthesis of natural hydroxycinnamide derived from Hippophae rhamnoides L. has been accom- plished. One-pot protection/deprotection and amidation of 4-hydroxycinnamic acid afforded the purposed cinnamide in good yield. The spectral data of synthesized cinnamide were in excellent agreement with the reported data. This synthetic pro- cedure would facilitate synthesis of the natural hydroxycinnamides, and their biological studies.
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KEYWORD
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Synthesis, one-pot reaction, hydroxycinnamide, Hippophae rhamnoides L.
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